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子宮珠蛋白重組兔單克隆抗體

產(chǎn)品貨號：

BN42158R
中文名稱：

子宮珠蛋白重組兔單克隆抗體
英文名稱：

Rabbit anti-SCGB1A1/Uteroglobin Monoclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價(jià)

備注
BN42158R-50ul

50ul

￥2020.00

交叉反應(yīng)：Human(predicted:Mouse,Rat) 推薦應(yīng)用：WB,ICC
BN42158R-100ul

100ul

￥3240.00

交叉反應(yīng)：Human(predicted:Mouse,Rat) 推薦應(yīng)用：WB,ICC

產(chǎn)品描述

英文名稱	Uteroglobin
中文名稱	子宮珠蛋白重組兔單克隆抗體
別名	blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell phospholipid binding protein; Clara cell phospholipid-binding protein; clara cell secretory protein; Clara cell specific 10 kD protein; Clara Cells 10 kDa Secretory Protein; OTTHUMP00000236107; Secretoglobin family 1A member 1; Secretoglobin, family 1A, member 1 (uteroglobin); UG; UGB; UP-1; UP1; Urinary Protein 1; Urine Protein 1; UTER_HUMAN; SCGB1A1; Utg.
研究領(lǐng)域	細(xì)胞生物免疫學(xué)
抗體來源	Rabbit
克隆類型	Monoclonal
克隆號	7G5
交叉反應(yīng)	Human, (predicted: Mouse, Rat, )
產(chǎn)品應(yīng)用	WB=1:500-1000 ICC=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	8kDa
細(xì)胞定位	分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	Recombinant human Uteroglobin:
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	Uteroglobin belongs to the family of secretoglobins and is a secreted protein product of nonciliated bronchiolar Clara cells. There is convincing data suggesting it has phospholipase A2 inhibitory activity, as well as, a number of other immunomodulatory features including inhibition of interferon gamma signalling and Th1 vs. Th2 lymphocyte regulation. It was proposed as a potential peripheral marker of respiratory epithelial injury and bronchial dysfunction. Clara Cell Protein 16 concentrations have been determined in both serum and bronchoalveolar lavage fluid in numerous studies since 1994. In serum, its increase is associated with age, asbestos, nitrogen chloride and ozone exposure, sarcoidosis and high PEEP ventilation. Decreased serum CC16 levels are found after pulmonary resection, in silica-exposed workers, smokers and in asthma. Decreased CC16 concentrations were also found in the amniotic fluid of fetuses suffering from pulmonary hypoplasia caused by various mechanisms (diaphragmatic hernia, diabetic fetopathy, Turner and Down syndrome). In pleural effusions, the CC16 concentration appears to be associated with its diffusion from the lung as evidenced by high CC16 levels in cardiac pleural congestion. Function: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Subunit: Homodimer; antiparallel disulfide-linked. Subcellular Location: Secreted. Tissue Specificity: Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways). Similarity: Belongs to the secretoglobin family. SWISS: P11684 Gene ID: 7356 Database links: Entrez Gene: 7356 Human Entrez Gene: 22287 Mouse Entrez Gene: 25575 Rat Omim: 192020 Human SwissProt: P11684 Human SwissProt: Q06318 Mouse SwissProt: P17559 Rat Unigene: 523732 Human Unigene: 2258 Mouse Unigene: 2206 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.